Author

A. M. Ellisdon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

C. Huang· 2 shared J. C. Whisstock· 2 shared L. D'Andrea· 2 shared M. L. Halls· 2 shared R. B. Schittenhelm· 2 shared C. A. Mitchell· 1 shared C. Bayly-Jones· 1 shared C. J. Lupton· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

C. Huang

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 18, 2021

The cryo-EM structure of the neurofibromin dimer reveals the molecular basis for von Recklinghausen disease

C. J. Lupton, C. Bayly-Jones, L. D'Andrea…·A. M. Ellisdon

This paper determines the cryo-EM structure of full-length NF1, revealing its autoinhibited conformation and providing insights into disease mechanisms and therapeutic strategies.

DOI 10.1101/2021.02.18.431788

humancryo-EM

𝕏 PostBluesky

BiochemistrybioRxivApr 11, 2020

Structural analysis of the PTEN:P-Rex2 signalling node reveals how cancer-associated mutations coordinate to hyperactivate Rac1

L. D'Andrea, C. M. Lucato, E. A. Marquez…·A. M. Ellisdon

The paper investigates the PTEN:P-Rex2 complex, identifying how cancer mutations disrupt its inhibitory function and hyperactivate Rac1 signaling.

DOI 10.1126/scisignal.abc4078

humanproteomics

𝕏 PostBluesky