Author

A. M. McDermott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:organoid / primary culture· 1 Organism:rat· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

J. D. Boerckel· 3 shared D. J. Kelly· 2 shared E. Alsberg· 2 shared J. H. Dawahare· 2 shared R. Tang· 2 shared S. Herberg· 2 shared A. Dikina· 1 shared A. McMillan· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBioengineering

J. D. Boerckel

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3 papers

Recent·Most cited

Effects of chondrogenic priming duration on mechanoregulation of engineered cartilage anlagen.

A. M. McDermott, E. A. Eastburn, J. D. Boerckel, D. J. Kelly

This study investigates how the duration of chondrogenic priming affects the response of engineered cartilage anlagen to dynamic mechanical compression, showing that priming duration modulates mechanical and biochemical outcomes.

bioRxiv · Sep 2, 2020Bioengineering

Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

S. Herberg, A. M. McDermott, P. N. Dang, D. S. Alt, R. Tang, J. H. Dawahare, D. Varghai, J.-Y. Shin, A. McMillan, A. Dikina, F. He, Y. B. Lee, Y. Cheng, K. Umemori, P. C. Wong, , E. Alsberg

The paper demonstrates that engineered human mesenchymal stem cell condensations with dual BMP-2 and TGF-β1 promote functional healing of critical-sized femoral defects via endochondral ossification, with healing rate and extent dependent on in vivo mechanical environment.

bioRxiv · Feb 26, 2019Bioengineering

Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues

A. M. McDermott, S. Herberg, D. E. Mason, H. B. Pearson, J. H. Dawahare, J. M. Collins, R. Tang, A. Patwa, M. W. Grinstaff, D. J. Kelly, E. Alsberg, J. D. Boerckel

This study shows that mechanical loading enhances bone regeneration through engineered mesenchymal condensations, mimicking endochondral ossification without heterotopic bone formation.

bioRxiv · Aug 15, 2018Bioengineering