Cell BiologybioRxivPreprint
Paracrine role for endothelial IGF-1 receptor in white adipocyte beiging
N. J. Haywood, K. Bridge, C. Luk…·M. Kearney
This study shows that reducing endothelial IGF-1R in nutrient excess promotes white adipocyte beiging, increases energy expenditure, and improves insulin sensitivity through paracrine malonic acid release.
DOI 10.1101/2021.12.01.470734