mTORC2 contributes to murine systemic autoimmunity
X. Zhou, H. Qi, M. Li, Y. Li, X. Zhu, S. Amin, A. Mariam, C. Diadhiou, A. Davidson, H. Zeng
This study shows mTORC2 promotes Tfh differentiation and disrupts Treg homeostasis, contributing to systemic autoimmunity, and suggests mTORC2 as a potential therapeutic target.
bioRxiv · Mar 27, 2021 · PreprintImmunology