Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings
K. L. Boswell, T. Watkins, E. M. Cale, J. Samsel, S. F. Andrews, D. R. Ambrozak, J. I. Driscoll, M. A. Messina, S. Narpala, C. S. Hopp, A. Cagigi, J. P. Casazza, T. Yamamoto, T. Zhou, W. R. Schief, , R. A. Koup
This study applies Bcl-6/Bcl-xL retroviral transduction to isolate antibodies and generate B cell clones from various B cell populations in healthy and infected individuals.
bioRxiv · Mar 29, 2022Immunology