Context-dependent functions of mitochondria protein quality control in lung
L. Xu, C. Tan, J. Barr, N. Talaba, J. Verheyden, J. S. Chin, S. Gaboyan, I. Advani, R. M. Elgamal, K. J. Gaulton, G. Lin, K. Afshar, E. Golts, A. Meier, L. C. Alexander, , X. Sun
This study shows that mitochondrial protein quality control via LONP1 is context-dependent in lung epithelial cells, affecting proliferation, differentiation, and migration through the integrated stress response.
bioRxiv · Dec 8, 2022 · PreprintCell Biology