B. Su

Non-invasive tracking of hippocampal theta oscillations

This paper shows that hippocampal theta oscillations can be detected and tracked non-invasively using MEG, validated across rodent and human datasets.

Single-molecule analysis reveals the phosphorylation of FLS2 governs its spatiotemporal dynamics and immunity

This study shows phosphorylation of FLS2 at Ser-938 affects its dynamics and immune response by directing it to AtRem1.3 nanodomains.

VPS34-IN1 inhibits cap-mediated translation and synergizes with STING to drive type-I IFN expression in human plasmacytoid DCs

VPS34-IN1 inhibits cap-mediated translation and enhances STING-driven type-I IFN expression in human plasmacytoid DCs by altering SGK3 recruitment and STING degradation.

Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models

This study shows that inhibiting SCD in breast cancer brain metastases induces lipotoxicity and enhances anti-tumor immunity, improving survival in mouse models.

Comparative single-cell regulome reveals evolutionary innovations in neural progenitor cells during primate corticogenesis

The paper compares single-cell regulomes of macaque and mouse neural progenitors with human data to identify evolutionary changes in cortex development.

Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses

This study compares molecular mechanisms and antiviral targets of Old and New World hantaviruses using human cell models and identifies potential therapeutic compounds.

Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development

The paper compares placental transcriptomes and histology between native Tibetans and Han migrants, finding sex-biased expression divergence and adaptive histological changes in male-infant placentas.

Generation of eco-friendly channel catfish, Ictalurus punctatus, harboring alligator cathelicidin gene with robust disease resistance by harnessing different CRISPR/Cas9-mediated systems

This study integrates an alligator cathelicidin gene into channel catfish using CRISPR/Cas9 to enhance disease resistance and control reproduction through hormone therapy.

Divergent MEK/ERK and AMPK signaling dictate lipogenic plasticity and dependence on fatty acid synthesis in Glioblastoma

This study identifies that MEK/ERK and AMPK signaling regulate lipogenic plasticity in Glioblastoma stem-like cells, influencing their dependence on fatty acid synthesis and response to DNLS inhibitors.

MEKK3-TGFβ crosstalk regulates inward arterial remodeling

This study identifies endothelial MEKK3 as a regulator of inward arterial remodeling through TGFβ-Smad2/3 signaling, leading to hypertension and atherosclerosis.

SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usage

This study evaluates antibody resistance and ACE2 usage in SARS-CoV-2 variants, finding SA501Y.V2 shows the highest resistance and expanded host range.

Fusobacterium nucleatum facilitates cetuximab resistance in colorectal cancer via the PI3K/AKT and JAK/STAT3 pathways

E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer

This study shows E-cadherin interacts with EGFR to hyper-activate ERK, promoting proliferation in breast cancer models and identifying a potential therapeutic target.

PEA polymer-coated nanotopography delivers solid-state BMP2, enhances mesenchymal stem cell adhesion, prevents bacterial biofilm formation and protects cells from quorum sensing virulence factors

Inferring MHC interacting SARS-CoV-2 epitopes recognized by TCRs towards designing T cell-based vaccines

This study infers SARS-CoV-2 epitopes recognized by TCRs through structural modeling and designs a T cell-based vaccine using immunoinformatics tools.

miR-200 deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts

This study shows that miR-200 deficiency in lung cancer cells promotes metastasis by activating cancer-associated fibroblasts through Notch signaling.

Effect of mechanical properties of monofilament twines on the catch efficiency of biodegradable gillnets.

This study compares the catch efficiency of biodegradable gillnets made from PBSAT resin with conventional nylon PA gillnets, finding lower efficiency for biodegradable nets despite matching tensile strength.

Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production

The paper identifies MRISC cells as a novel intestinal stem cell niche that produces R-spondin1 via Map3k2 signaling to promote intestinal regeneration after damage.

Fate mapping via Ms4a3 expression history traces monocyte-derived cells

The paper identifies Ms4a3 as a marker for tracking monocyte-derived cells and quantifies their contribution to tissue-resident macrophages during homeostasis and inflammation.

Electrospun Cellulose-Silk Composite Nanofibres Direct Mesenchymal Stem Cell Chondrogenesis in the Absence of Biological Stimulation

This paper develops electrospun cellulose-silk composite nanofibers that direct chondrogenic differentiation of hMSCs without growth factors.

Structural and biochemical characterization on the cognate and heterologous interactions of the MazEF-mt9 TA system

This study characterizes the structural and biochemical interactions of the MazEF-mt9 TA system in M. tb, revealing its cognate and heterologous antitoxin binding and its role in stress adaptation.

Spatio-temporal variability of soil nutrients and the responses of growth during growth stages of winter wheat in the north of China

This study analyzes soil nutrient variability and its impact on winter wheat growth stages in northern China under traditional tillage, finding nutrient content and growth correlations change over time.