Author

A. Mostafa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Chang· 1 shared A. Ganguli· 1 shared A. Iqbal· 1 shared A. M. Khalil· 1 shared A. Michelucci· 1 shared A. Sohail· 1 shared B. T. Cunningham· 1 shared C. A. Guzman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Chang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Potent neutralization by a receptor binding domain monoclonal antibody with broad specificity for SARS-CoV-2 JN.1 and other variants

M. S. Piepenbrink, A. M. Khalil, A. Chang, A. Mostafa, M. Basu, S. Sarkar, S. Panjwani, Y. H. Ha, Y. Ma, C. Ye, Q. Wang, T. J. Green, J. L. Kizziah, N. B. Erdmann, P. A. Goepfert, , J. J. Kobie

This study develops a monoclonal antibody that broadly neutralizes multiple SARS-CoV-2 variants, including JN.1, and shows its protective efficacy in mice.

bioRxiv · Apr 27, 2024 · PreprintImmunology

Chlorpheniramine Maleate Displays Multiple Modes of Antiviral Action Against SARS-CoV- 2: A Mechanistic Study

Y. A. M. M. Elshaier, A. Mostafa, F. Valerio-Pascua, M. L. Tesch, J. M. Costin, F. F. Rahaghi

This study shows that Chlorpheniramine Maleate inhibits SARS-CoV-2 by blocking viral adsorption, replication, and direct inactivation through interactions with key viral proteins.

bioRxiv · Aug 28, 2023 · PreprintPharmacology & Toxicology

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

A. Sohail, A. Iqbal, N. Sahini, M. Tantawy, M. Winterhoff, R. Geffers, T. Ebensen, K. Schughart, M. Pils, F. Chen, C. A. Guzman, M. Preusse, S. Pleschka, A. Mostafa, C. Falk, , F. Pessler

This study shows itaconate and its derivatives reduce interferon responses and inflammation in influenza A virus infection without increasing viral replication.

bioRxiv · Jan 20, 2021Immunology

Rapid Isothermal Amplification and Portable Detection System for SARS-CoV-2

A. Ganguli, A. Mostafa, J. Berger, M. Aydin, F. Sun, E. Valera, B. T. Cunningham, W. P. King, R. Bashir

This paper develops a rapid, portable RT-LAMP assay for SARS-CoV-2 detection with performance comparable to RT-PCR, using a smartphone-based reader for point-of-care testing.

bioRxiv · May 21, 2020Bioengineering