Author

A. Olive

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. M. Ankley· 2 shared A. E. Lord· 1 shared A. Worley· 1 shared C. A. Kulicke· 1 shared C. Lemon· 1 shared C. M. Heisler· 1 shared D. A. Lewinsohn· 1 shared D. M. Lewinsohn· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

L. M. Ankley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation

C. A. Kulicke, G. M. Swarbrick, N. A. Ladd, M. Cansler, M. Null, A. Worley, C. Lemon, T. Ahmed, J. Bennett, T. N. Lust, C. M. Heisler, M. E. Huber, J. R. Krawic, L. M. Ankley, S. K. McBride, , M. J. Harriff

The paper demonstrates that delivering MR1 monomers loaded with 5-OP-RU enables ligand exchange to host MR1, leading to MR1T cell activation.

bioRxiv · Jul 11, 2022Immunology

FLAMs: A self-replicating ex vivo model of alveolar macrophages for functional genetic studies

S. Thomas, K. Wierenga, J. Pestka, A. Olive

This paper develops FLAMs, a self-replicating model of alveolar macrophages, enabling functional genetic studies to identify genes regulating AM maintenance and function.

bioRxiv · Dec 12, 2021 · PreprintImmunology

A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation

M. C. Kiritsy, L. M. Ankley, J. D. Trombley, G. P. Huizinga, A. E. Lord, P. Orning, R. Elling, K. A. Fitzgerald, A. Olive

This study identifies new regulators of IFNγ-induced MHCII in macrophages using CRISPR screens, revealing pathways involving GSK3β and MED16 that are critical for CD4+ T cell activation.

bioRxiv · Aug 12, 2020Immunology