Author

J. D. Trombley

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. E. Lord· 1 shared A. Olive· 1 shared G. P. Huizinga· 1 shared K. A. Fitzgerald· 1 shared L. M. Ankley· 1 shared M. C. Kiritsy· 1 shared P. Orning· 1 shared R. Elling· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. E. Lord

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1 paper

Recent·Most cited

ImmunologybioRxivAug 12, 2020

A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation

M. C. Kiritsy, L. M. Ankley, J. D. Trombley…·A. Olive

This study identifies new regulators of IFNγ-induced MHCII in macrophages using CRISPR screens, revealing pathways involving GSK3β and MED16 that are critical for CD4+ T cell activation.

DOI 10.7554/elife.65110

mousebulk RNA-seq

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