Author

A. P. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. L. Fink· 1 shared A. L. Mueller· 1 shared A. Pekosz· 1 shared A. Z. Lau· 1 shared C. H. Cunningham· 1 shared G. Reed· 1 shared H. B. Larman· 1 shared H. Liu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. L. Fink

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Greater breadth of vaccine-induced immunity in females than males is mediated by increased antibody diversity in germinal center B cells

R. L. Ursin, S. Dhakal, H. Liu, S. Jayaraman, H.-S. Park, H. R. Powell, M. L. Sherer, K. E. Littlefield, A. L. Fink, Z. Ma, A. L. Mueller, A. P. Chen, Y. A. Woldetsadik, P. J. Gearhart, H. B. Larman, , S. L. Klein

This study shows that female mice have stronger and more diverse antibody responses to influenza vaccination, leading to better protection against mutant viruses due to increased germinal center B cell activity.

bioRxiv · May 31, 2022Immunology

Cardiac metabolic imaging using hyperpolarized lactate as a substrate

A. Z. Lau, A. P. Chen, C. H. Cunningham

This study demonstrates the use of hyperpolarized lactate as a substrate for cardiac metabolic imaging in pigs, showing comparable signal-to-noise ratios to pyruvate but with lower SNR due to metabolic conversion steps.

bioRxiv · Dec 4, 2020Biophysics

Distinguishing Closely Related Pancreatic Cancer Subtypes In Vivo by 13C Glucose MRI without Hyperpolarization

S. Kishimoto, J. R. Brender, S. Matsumoto, T. Seki, N. Oshima, H. Merkle, G. Reed, A. P. Chen, J. H. Ardenkjaer-Larsen, J. Munasinghe, K. Saito, K. Yamamoto, P. Choyke, J. Mitchell, M. C. Krishna

The paper distinguishes closely related pancreatic cancer subtypes in vivo using 13C glucose MRI without hyperpolarization by detecting metabolic differences through tensor decomposition.

bioRxiv · Jan 4, 2019 · PreprintCancer Biology