A. Puhar

Extracellular ATP is an environmental cue in bacteria

This study shows that extracellular ATP (eATP) acts as an environmental cue for bacteria, altering their transcription, metabolism, and virulence.

CRISPR-Cas guided mutagenesis of chromosome and virulence plasmid in Shigella flexneri by cytosine base editing

This paper develops a CRISPR-Cas base editing method to generate targeted loss-of-function mutants in Shigella flexneri with high efficacy and throughput.

The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy

This study shows that Vibrio cholerae toxin MakA induces noncanonical autophagy, which inhibits canonical autophagy and immune responses like IL-1β secretion.

The generation of plasma cells and CD27-IgD- B cells during Hantavirus infection are associated with distinct pathological findings

This study links plasma cell and CD27-IgD- B cell generation during Hantavirus infection to distinct pathological features in HFRS.

Complete genome sequence and annotation of the laboratory reference strain Shigella flexneri serovar 5a M90T and genome-wide transcriptional start site determination

The paper provides the complete genome sequence of Shigella flexneri serotype 5a M90T and identifies genome-wide transcriptional start sites, offering tools for systems biology and genetic manipulation.