K. Persson

Regulation of lactose and galactose growth: Insights from a unique metabolic gene cluster in Candida intermedia

This study identifies three gene clusters in Candida intermedia responsible for lactose and galactose metabolism, revealing a unique regulatory network distinct from other yeasts.

Adaptation of the yeast gene knockout collection is near-perfectly predicted by fitness and diminishing return epistasis

This study shows that fitness predicts adaptation dynamics in yeast gene knockouts under arsenic exposure, with diminishing return epistasis explaining the predictability.

Protein-lipid interaction at low pH induces oligomerisation of the MakA cytotoxin from Vibrio cholerae

This study shows that MakA, a Vibrio cholerae toxin, forms tube-like structures in acidic conditions through protein-lipid interactions, revealing a novel mechanism of membrane tubulation.

A tripartite cytolytic toxin formed by Vibrio cholerae proteins with flagellum-facilitated secretion

This paper identifies a tripartite cytolytic toxin from Vibrio cholerae, showing that MakA/B/E proteins are secreted via flagella and form pores in membranes, contributing to bacterial virulence.

Panacea: a hyperpromiscuous antitoxin protein domain for the neutralisation of diverse toxin domains

The paper identifies and validates a hyperpromiscuous antitoxin domain, Panacea, capable of neutralizing diverse toxin domains across microbial and bacteriophage TA systems.

High-resolution model of Arabidopsis Photosystem II reveals the structural consequences of digitonin-extraction

The paper presents a high-resolution Cryo-EM structure of Arabidopsis PSII and identifies structural features and detergent effects on its stability.

Genetically controlled mtDNA editing prevents ROS damage by arresting oxidative phosphorylation

The paper shows yeast cells use genetically controlled mtDNA editing to prevent ROS damage by shutting down oxidative phosphorylation.

The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy

This study shows that Vibrio cholerae toxin MakA induces noncanonical autophagy, which inhibits canonical autophagy and immune responses like IL-1β secretion.

Domestication reprogrammed the budding yeast life cycle

This study shows that domestication of budding yeast reprogrammed its life cycle, favoring survival as quiescent cells over sexual reproduction and enhancing fermentative traits.

The Dps4 from Nostoc punctiforme ATCC 29133 is a member of His-type FOC containing Dps protein class that can be broadly found among cyanobacteria

This study presents the crystal structure and functional analysis of NpDps4, a Dps protein from Nostoc punctiforme, revealing a novel His-type FOC that differs from canonical Dps proteins.