Author

A. Purkayastha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Konda· 3 shared G. Garcia· 3 shared V. Arumugaswami· 3 shared A. Mulay· 2 shared B. Gomperts· 2 shared B. N. Gomperts· 2 shared B. R. Stripp· 2 shared C. Sen· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

B. Konda

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 22, 2022

Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models

A. Petcherski, M. Sharma, S. Satta…·T. Kelesidis

Mitoquinone mesylate shows antiviral and anti-inflammatory effects against SARS-CoV-2 in preclinical models.

DOI 10.1101/2022.02.22.481100

mouseexperimental assay

𝕏 PostBluesky

Cell BiologyNature MedicinePeer-reviewedMay 6, 2021

A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis

G. Carraro, J. Langerman, S. Sabri…·B. N. Gomperts

The paper uses single-cell transcriptomics to analyze proximal airway epithelium in CF and healthy donors, identifying molecular changes linked to CF pathogenesis.

DOI 10.1038/s41591-021-01332-7

𝕏 PostBluesky

Cell BiologybioRxivJul 28, 2020

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stemcell-derived airway repair response

A. Purkayastha, C. Sen, G. Garcia…·B. N. Gomperts

This study shows that cigarette smoke exposure increases SARS-CoV-2 infection severity in airway cultures by reducing interferon response and ABSC proliferation.

DOI 10.1016/j.stem.2020.11.010

𝕏 PostBluesky

Cell BiologybioRxivJun 29, 2020

SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery

A. Mulay, B. Konda, G. Garcia…·B. Stripp

The paper develops a primary human lung epithelium infection model to study SARS-CoV-2 pathobiology and screen drugs for COVID-19.

DOI 10.1016/j.celrep.2021.109055

humanexperimental assay

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Scientific Communication & EducationbioRxivNov 5, 2018

Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results

G. Alterovitz, D. A. Dean, C. Goble…·R. Mazumder

The paper introduces the BioCompute framework to standardize genomic data reporting, enabling reproducibility and interoperability in precision medicine.

DOI 10.1371/journal.pbio.3000099

whole-genome sequencingexperimental assay

𝕏 PostBluesky