Author

L. Cabel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Krucker· 2 shared C. S. Groeneveld· 2 shared E. Chapeaublanc· 2 shared F. Dufour· 2 shared F. Radvanyi· 2 shared F.-C. Bidard· 2 shared I. Bernard-Pierrot· 2 shared I. Bieche· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

C. Krucker

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Author profile →

4 papers

Recent·Most cited

Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies.

H. Lang, C. Beraud, L. Cabel, M. Lassalle, J. Fontugne, C. Krucker, F. Dufour, C. S. Groeneveld, V. Dixon, X. Meng, A. Kamoun, E. Chapeaublanc, A. De Reynies, X. Game, P. Rischmann, , T. Massfelder

The paper develops patient-derived xenografts (PDXs) for bladder and ureteral cancers, identifies molecular subtypes, and shows that combined FGFR/EGFR inhibition is more effective than single-agent therapy for FGFR3-mutant tumors.

Frontiers in Oncology · Aug 11, 2022Peer-reviewedCancer Biology

Epigenomic mapping identifies a super-enhancer repertoire that regulates cell identity in bladder cancers through distinct transcription factor networks

H. Neyret-Kahn, J. Fontugne, X.-Y. Meng, C. S. Groeneveld, L. Cabel, T. Ye, E. Guyon, C. Krucker, F. Dufour, E. Chapeaublanc, A. Rapinat, D. C. B. Jeffery, Y. Neuzillet, T. Lebret, D. Gentien, , F. Radvanyi

The paper identifies super-enhancer networks regulating bladder cancer subtypes through transcription factors, showing their role in cell identity and inflammatory response suppression.

bioRxiv · Jan 11, 2022Cancer Biology

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

Y. Liu, T.-Y. Liu, D. E. Weinberg, B. W. White, C. J. De La Torre, C. L. Tan, A. D. Schmitt, S. Selvaraj, V. Tran, L. C. Laurent, L. Cabel, F.-C. Bidard, G. Putcha, I. S. Haque

The paper shows that fragment length patterns in cell-free DNA reflect in vivo chromatin organization and can identify tissues-of-origin.

bioRxiv · Oct 23, 2019 · PreprintGenomics

A single droplet digital PCR for ESR1 activating mutations detection in plasma

E. Jeannot, L. Darrigues, M. Michel, M.-H. Stern, J.-Y. Pierga, A. Rampanou, S. Melaabi, C. Benoist, I. Bieche, A. Vincent-Salomon, R. El Ayachy, A. Noret, N. Epaillard, L. Cabel, F.-C. Bidard, C. Proudhon

This paper develops a multiplex droplet digital PCR assay for detecting ESR1 activating mutations in plasma, showing high sensitivity and concordance with NGS data.

bioRxiv · Jan 8, 2019Cancer Biology