BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
DNA origami demonstrate the unique stimulatory power of single pMHCs as T-cell antigens
J. Hellmeier, R. Platzer, A. S. Eklund…·E. Sevcsik
The paper demonstrates that single pMHCs can robustly stimulate T-cells as isolated entities, identifying the minimal requirements for effective TCR-triggering.
DOI 10.1073/pnas.2016857118