Cancer BiologybioRxiv
Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA
C. D. James, A. Youssef, A. Tadimari Prabhakar…·I. M. Morgan
This paper shows HPV16 replication converts SAMHD1 into a homologous recombination factor by phosphorylation, enhancing its recruitment to viral DNA and reducing replication.
DOI 10.1128/jvi.00826-24