ImmunologybioRxivPreprint
Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TIMBIM4 safeguards IgG1+ GC B cell positive selection
L. Zhang, A. Toboso-Navasa, A. Gunawan…·D. P. Calado
This study identifies MIZ1-TMBIM4 as a mechanism safeguarding IgG1+ GC B cell positive selection by regulating Ca2+ mobilization and preventing mitochondrial dysfunction.
DOI 10.1101/2023.07.18.549490