Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells
J. Bohme, N. Martinez, S. Li, A. Lee, M. Marzuki, A. Tizazu, D. Ackart, J. Frenkel, A. Todd, E. Lachmandas, J. Lum, F. Shihui, T. P. Ng, B. Lee, A. Larbi, , A. Singhal
This study shows metformin improves anti-mycobacterial responses by enhancing metabolic and functional properties of CD8+ T cells in mice and humans.
bioRxiv · Aug 26, 2020Immunology