Author

F. Shihui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Lee· 3 shared A. Singhal· 3 shared B. Lee· 2 shared H. Kornfeld· 2 shared J. Lum· 2 shared M. Marzuki· 2 shared A. Larbi· 1 shared A. Rathee· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

A. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ly6G+Granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis

P. Sharma, R. D. Sharma, B. Sarkar, V. Panwar, M. Das, L. Singh, N. Jain, S. Chaturvedi, L. Mehra, A. Rathee, S. Sharma, F. Shihui, A. Lee, P. N. Kumar, P. Das, , D. Kumar

This study identifies IL-17 and COX2 as negative regulators of protective immunity in tuberculosis, showing that Ly6G+ granulocytes are a major source of IL-17 and their inhibition reduces bacterial burden and pathology.

bioRxiv · Oct 5, 2023Immunology

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

D. Chaudhary, M. Marzuki, A. Lee, R. Bouzeyen, A. Singh, T. P. Gosain, S. Kidwai, C. Grady, K. Tsotetsi, K. Chawla, F. Shihui, J. Lum, S. K. Gupta, N. Agarwal, L. Tsenova, , A. Singhal

This study identifies disulfiram as a novel inhibitor of Mtb's methionine biosynthesis, showing anti-tubercular effects through redox disruption and immune modulation.

bioRxiv · Sep 1, 2020 · PreprintMicrobiology

Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells

J. Bohme, N. Martinez, S. Li, A. Lee, M. Marzuki, A. Tizazu, D. Ackart, J. Frenkel, A. Todd, E. Lachmandas, J. Lum, F. Shihui, T. P. Ng, B. Lee, A. Larbi, , A. Singhal

This study shows metformin improves anti-mycobacterial responses by enhancing metabolic and functional properties of CD8+ T cells in mice and humans.

bioRxiv · Aug 26, 2020Immunology