BiochemistrybioRxiv
Structural basis for activation of DNMT1
A. Kikuchi, H. Onoda, K. Yamaguchi…·K. Arita
This study determines the cryo-EM structure of DNMT1 bound to hemimethylated DNA and ubiquitinated histone H3, revealing a mechanism for its activation.
DOI 10.1038/s41467-022-34779-4