Author
University at Buffalo, State University of New York
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Alexsandra P. Lenhard, Chloe Picciano, Miles J Stefko…·Elsa N. Bou Ghanem
This study identifies CD73 as a regulator of neutrophil responsiveness to type I interferon, which impairs antibacterial responses during secondary pneumococcal pneumonia following influenza A virus infection.
Michael C. Battaglia, Manmeet Bhalla, Brandon J. Marzullo…·Elsa N. Bou Ghanem
This study shows that aging leads to senescent-like neutrophils in mice, which have reduced antimicrobial function and altered transcriptional responses to Streptococcus pneumoniae.
Shaunna R. Simmons, Alexsandra P. Lenhard, Michael C. Battaglia, Elsa N. Bou Ghanem
This study shows that adenosine 2B receptor signaling impairs neutrophil killing of antibody-opsonized pneumococci in young vaccinated mice, reducing vaccine efficacy, but not in aged mice.
Shaunna R. Simmons, Sydney E. Herring, Essi Y. I. Tchalla…·Elsa N. Bou Ghanem
This study shows that activating A1 adenosine receptors in aged mice enhances early neutrophil recruitment to the lungs during Streptococcus pneumoniae infection, improving bacterial control.