Anna Blumental‐Perry

This study shows ATF6α regulates lung aging and remodeling in specific cell types, with distinct effects on epithelial mitochondrial function and pericyte fibrosis.

This study shows that aging leads to senescent-like neutrophils in mice, which have reduced antimicrobial function and altered transcriptional responses to Streptococcus pneumoniae.

This study identifies a human homologue of a mitochondrial noncoding RNA that translocates to the nucleus and enhances mitochondrial bioenergetics in response to cigarette smoke, but its levels decline in chronic obstructive pulmonary disease.