Author

B. A. Santo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Z. Rosenberg· 3 shared J. B. Kopp· 3 shared P. Sarder· 3 shared B. A. Jones· 2 shared C. A. Winkler· 2 shared K. Myakala· 2 shared K. Z. Latt· 2 shared M. Levi· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPathology

A. Z. Rosenberg

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Author profile →

3 papers

Recent·Most cited

APOL1 kidney risk variants in glomerular diseases modeled in transgenic mice

T. Yoshida, K. Z. Latt, B. A. Santo, S. Shrivastav, Y. Zhao, P. Fenaroli, J.-Y. Chung, S. M. Hewitt, V. M. Tutino, P. Sarder, A. Z. Rosenberg, C. A. Winkler, J. B. Kopp

This paper uses two transgenic mouse models to study APOL1 risk variants' effects on glomerular disease, identifying shared and distinct transcriptional changes in podocytes.

bioRxiv · Mar 27, 2023Pathology

PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

T. Yoshida, K. Z. Latt, A. Z. Rosenberg, B. A. Santo, K. Myakala, Y. Ishimoto, Y. Zhao, S. Shrivastav, B. A. Jones, X. Yang, X. Wang, V. M. Tutino, P. Sarder, M. Levi, K. Okamoto, , J. B. Kopp

This study shows that PKR inhibition reduces mitochondrial dysfunction and ameliorates HIV-associated nephropathy in transgenic mice using single-nucleus and bulk RNA-seq.

bioRxiv · Oct 3, 2022Pathology

PodoCount: A robust, fully automated whole-slide podocyte quantification tool

B. A. Santo, D. Govind, P. Daneshpajouhnejad, X. Yang, X. X. Wang, K. Myakala, B. A. Jones, M. Levi, J. B. Kopp, L. J. Niedernhofer, D. Manthey, K. C. Moon, S. S. Han, A. Z. Rosenberg, P. Sarder

PodoCount quantifies podocytes in kidney tissues with high accuracy, showing strong correlation with disease diagnosis and clinical outcomes in both murine models and human diabetic nephropathy.

bioRxiv · Apr 27, 2021Pathology