L. Cook

Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates

This study identifies proteomic subtypes and recurrence patterns in IDH-wildtype glioblastoma using tissue and serum samples, revealing prognostic markers and proteomic plasticity in recurrent tumors.

Are asymmetric inheritance systems an evolutionary trap? Transitions in the mechanism of genome loss in the scale insect family Eriococcidae

The paper investigates whether asymmetric inheritance systems like paternal genome elimination (PGE) in Eriococcidae scale insects are evolutionary traps by examining transitions to Mendelian inheritance.

AN INULIN-TYPE FRUCTAN ENRICHED EXCLUSIVE ENTERAL NUTRITION FORMULA SUPPRESSES COLITIS THROUGH GUT MICROBIOME MODULATION AND PROMOTING EXPANSION OF ANTI-INFLAMMATORY T CELL SUBSETS

This paper shows that an inulin-type fructan-enriched enteral nutrition formula reduces colitis in mice by modulating the gut microbiome and increasing anti-inflammatory T cell subsets.

Size Matters: Metastatic cluster size and stromal recruitment in the establishment of successful prostate cancer to bone metastases

This study uses a computational model to show that prostate cancer metastases to bone require optimal cluster size and stromal cell recruitment for successful establishment.

Genomic and proteomic analysis of Human herpesvirus 6 reveals distinct clustering of acute versus inherited forms and reannotation of reference strain

This study sequences HHV-6B and iciHHV-6 genomes, identifies geographic clustering and recombination in active infections, and reannotates the HHV-6B genome using transcriptomics and proteomics.

Standard Issue: Copy number heterogeneity of JC virus standards discovered through next-generation sequencing

This study identifies copy number heterogeneity in JC virus standards using next-generation sequencing, revealing significant genomic coverage variation due to large deletions.