Author

B. Cai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 2 Microbiology· 2 Pathology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:mouse· 6 Research Focus:host-pathogen & immune response· 5 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

M. Gao· 2 shared X. Huang· 2 shared A. C. Marquez· 1 shared A. Chadha· 1 shared A. F. Rosenberg· 1 shared A. J. Seymour· 1 shared A. Yurdagul· 1 shared B. A. Vallance· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersImmunology

M. Gao

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11 papers

Recent·Most cited

Spatial kinetics and immune control of murine cytomegalovirus infection in the salivary glands

C. M. Byrne, A. C. Marquez, B. Cai, D. Coombs, S. Gantt

This study investigates the spatial kinetics and immune control of murine cytomegalovirus infection in salivary glands, identifying immune correlates and constructing mathematical models to understand viral spread and control.

bioRxiv · Feb 22, 2024Microbiology

Cholesterol-associated Locus EHBP1 Protects against NASH Fibrosis

F. Ma, M. Longo, X. Huang, M. Meroni, S. Prakash, E. Paolini, D. Bhattacharya, S. Wang, X. Wang, S. Mughal, S. Hussain, S. Anand, A. Yurdagul, O. Rom, P. Dongiovanni, , B. Cai

This study identifies EHBP1 as a protective locus against NASH fibrosis by regulating cholesterol metabolism and interacting with other cholesterol-related genes.

bioRxiv · Jul 8, 2023 · PreprintPathology

A novel subset of colonocytes targeted by Citrobacter rodentium elicits epithelial MHCII-restricted help from CD4 T cells

C. Zindl, C. G. Wilson, A. Chadha, B. Cai, S. Harbour, Y. Nagaoka-Kamata, R. Hatton, M. Gao, D. Figge, C. Weaver

The paper identifies a novel subset of colonocytes targeted by Citrobacter rodentium that require MHCII-restricted help from CD4 T cells for IL-22 signaling and immune protection.

bioRxiv · May 3, 2023 · PreprintImmunology

Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing

S. Shin, L. G. Brunel, B. Cai, D. Kilian, J. G. Roth, A. J. Seymour, S. C. Heilshorn

This paper introduces a 3D bioprinting method called GUIDE-3DP to create perfusable, branched vascular networks with precise control over geometry and vessel sizes.

bioRxiv · Apr 2, 2023Bioengineering

Pseudomonas syringae effector AvrE associates with plant membrane nanodomains and binds phosphatidylinositides in vitro

X. Xin, L. Kinch, B. Cai, B. C. Paasch, B. Kvitko, N. V. Grishin, S. Y. He

bioRxiv · Jul 8, 2021 · PreprintPathology

A Non-redundant Role for T cell-derived IL-22 in Antibacterial Defense of Colonic Crypts

C. T. Weaver, C. L. Zindl, S. J. Witte, V. A. Laufer, M. Gao, Z. Yue, D. J. Silberger, S. N. Harbour, J. R. Singer, D. Pham, C. E. Moseley, B. Cai, H. Turner, F. E. Lund, B. A. Vallance, , R. D. Hatton

This study shows that T cell-derived IL-22 is essential for antibacterial defense and damage control in intestinal crypts, despite ongoing ILC3-derived IL-22 production.

bioRxiv · May 11, 2021 · PreprintImmunology

Mammalian-unique eIF4E2 maintains GSK3β proline kinase activity to resist senescence against hypoxia

M. zhang, L. Sun, D. He, J. Chen, Z. Dong, H. Liang, Y. Cao, B. Cai, H. Yang

This paper identifies a mammalian-unique eIF4E2-GSK3β pathway that prevents senescence and protects against hypoxia by maintaining p53 phosphorylation.

bioRxiv · Oct 20, 2020 · PreprintCell Biology

CelLEVITAS: Label-free, rapid sorting and enrichment of live cells via magnetic levitation

E. K. Chin, C. A. Grant, M. G. Ogut, B. Cai, N. G. Durmus

CelLEVITAS sorts and enriches live cells without labels, achieving high purity and viability in 30 minutes.

bioRxiv · Jul 27, 2020 · PreprintBioengineering

Transcriptomic analyses revealed the effect of Funneliformis mosseae on differentially expressed genes in Fusarium oxysporum

X.-q. Zhang, L. Bai, N. Guo, B. Cai

This study investigates how F. mosseae affects gene expression in F. oxysporum-infected soybean roots, identifying differentially expressed genes and their biological functions.

bioRxiv · May 28, 2020Ecology

Moxifloxacin efficacy against Mycobacterium abscessus in vivo using zebrafish model

W. Nie, S. Gao, T. Teng, W. Zhou, Y. Shang, W. Jing, W. Shi, Q. Wang, X. Huang, B. Cai, J. Wang, J. Wang, R. Guo, Q. Ge, L. Nie, , N. Chu

This study evaluates moxifloxacin efficacy against Mycobacterium abscessus in a zebrafish model, finding limited in vivo activity despite good in vitro results.

bioRxiv · Dec 5, 2019 · PreprintMicrobiology

Membrane association of VAMP2 SNARE motif in cells and its regulation by different lipid phases of synaptic vesicle membrane

C. Wang, J. Tu, S. Zhang, B. Cai, Z. Liu, S. Hou, Z. Liu, J. Diao, Z.-J. Zhu, C. Liu, D. Li

This study investigates how lipid phases in synaptic vesicle membranes regulate the structure and function of the VAMP2 SNARE motif using in-cell NMR and lipidomic profiling.

bioRxiv · Mar 24, 2019 · PreprintBiophysics