Author

B. D. Stein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

L. C. Cantley· 3 shared D. Wu· 2 shared E. E. Gardner· 2 shared H. Varmus· 2 shared R. E. Moellering· 2 shared A. Ducret· 1 shared A. M. Laughney· 1 shared B. LaSarre· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

L. C. Cantley

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Author profile →

4 papers

Recent·Most cited

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

E. E. Gardner, E. M. Earlie, K. Li, J. Thomas, M. J. Hubisz, B. D. Stein, C. Zhang, L. C. Cantley, A. M. Laughney, H. Varmus

The paper models histological transformation of lung cancer and identifies neuroendocrine-specific tolerance to Myc as an oncogenic driver.

bioRxiv · Jun 21, 2023Cancer Biology

Non-conserved metabolic regulation by LKB1 distinguishes human and mouse lung adenocarcinoma

B. D. Stein, J. R. Ferrarone, E. E. Gardner, J. W. Chang, D. Wu, Q. Chen, P. E. Hollstein, M. Yuan, R. J. Liang, J. S. Coukos, M. Sindelar, B. Ngo, S. S. Gross, R. J. Shaw, J. M. Asara, , L. C. Cantley

This study identifies a metabolic divergence between human and mouse lung adenocarcinomas due to LKB1-dependent regulation of TPI1 phosphorylation, highlighting limitations of mouse models for studying human cancer.

bioRxiv · Oct 1, 2021 · PreprintCancer Biology

Diverse Hotspot Thermal Profiling Methods Detect Phosphorylation-Dependent Changes in Protein Stability

B. D. Stein, J. X. Huang, D. Wu, L. C. Cantley, R. E. Moellering

The paper compares two HTP methods, finding that LFE-HTP improves proteoform coverage and detects novel phosphorylation sites affecting protein stability.

bioRxiv · May 1, 2021 · PreprintBiochemistry

Diverse spatial organization of photosynthetic membranes among purple nonsulfur bacteria

B. LaSarre, D. T. Kysela, B. D. Stein, A. Ducret, Y. V. Brun, J. B. McKinlay

The paper examines the spatial organization of photosynthetic membranes in purple nonsulfur bacteria, revealing species-specific patterns and their evolutionary implications.

bioRxiv · Jan 17, 2018Microbiology