Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
N. Nader, L. Assaf, L. Zarif…·K. Machaca
This study identifies ABHD2 as an essential co-receptor for mPRβ to trigger meiosis via PLA2 activity in Xenopus oocytes.
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3 papers
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N. Nader, L. Assaf, L. Zarif…·K. Machaca
This study identifies ABHD2 as an essential co-receptor for mPRβ to trigger meiosis via PLA2 activity in Xenopus oocytes.
B. D. Stein, J. R. Ferrarone, E. E. Gardner…·L. C. Cantley
This study identifies a metabolic divergence between human and mouse lung adenocarcinomas due to LKB1-dependent regulation of TPI1 phosphorylation, highlighting limitations of mouse models for studying human cancer.
A. Halama, M. Kulinski, S. S. Dib…·K. Suhre
The paper shows that inhibiting glutaminolysis in cancer cells leads to lipid catabolism and autophagy, which promote survival, and that combined inhibition of both pathways can induce cell death.