Author

B. Blum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

A. Emili· 3 shared F. Douam· 3 shared A. K. O'Connell· 2 shared D. Kenney· 2 shared J. H. Connor· 2 shared M. Bosmann· 2 shared M. Ericsson· 2 shared M. Saeed· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

A. Emili

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Platelet proteome analysis reveals an early hyperactive phenotype in SARS-CoV-2-infected humanized ACE2 mice

S. Subramaniam, R. M. Hekman, A. Jayaraman, A. K. O'Connell, P. Montanaro, B. Blum, D. Kenney, M. Ericsson, K. Ravid, N. A Crossland, A. Emili, F. Douam, M. Bosmann

This paper uses proteomics to analyze platelet changes in SARS-CoV-2-infected humanized mice, finding early activation of coagulation and complement pathways.

bioRxiv · Aug 19, 2021 · PreprintImmunology

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology

SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway

D.-Y. Chen, N. Khan, B. J. Close, R. K. Goel, B. Blum, A. H. Tavares, D. Kenney, H. L. Conway, J. K. Ewoldt, S. Kapell, V. C. Chitalia, N. A. Crossland, C. S. Chen, D. N. Kotton, S. C. Baker, , M. Saeed

This study identifies SARS-CoV-2 inhibition of the JAK-STAT pathway as a mechanism to suppress interferon signaling across diverse cell types.

bioRxiv · Oct 27, 2020 · PreprintMicrobiology