T. Ott

Effects of parity and early pregnancy on peripheral blood leukocytes in dairy cattle

This study examines how parity and early pregnancy affect immune cell populations and function in dairy cattle, finding differences in immune responses between heifers and cows that may explain reduced fertility.

Effects of conceptus proteins on endometrium and blood leukocytes of dairy cattle using transcriptome and meta-analysis

This study examines the effects of IFNT and PAG on endometrial and blood leukocyte transcriptomes in dairy cattle, identifying differentially expressed genes and their biological functions.

Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection

This study shows that CPK3 and its substrate REM1.2 interact dynamically at the plasma membrane, influencing viral propagation in Arabidopsis.

Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in Medicago truncatula

The paper identifies a cell-cycle exit decision in Medicago truncatula root cortex cells that facilitates transcellular infection by rhizobia.

Transcellular progression of infection threads in Medicago truncatula roots is controlled by locally confined cell wall modifications

The paper investigates how rhizobia move through Medicago truncatula root cells by analyzing the role of SyPME and NPL in cell wall modifications during infection thread progression.

RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections

This study identifies RPG as a critical protein for infection thread formation and cellular polarization during rhizobial infections in Medicago truncatula.

Remorin proteins serve as membrane topology scaffolds in plants

The paper shows remorin proteins stabilize membrane tubules and curvature during symbiotic infections in plants.

Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome

A small molecule screen identifies tyrosine kinase inhibitors that cause lysosomal damage, leading to cell lysis and NLRP3 inflammasome activation via K+ efflux.

Apparent sunk cost effect in rational agents

The paper challenges the sunk cost fallacy in decision-making by showing rational agents can exhibit similar behavior without relying on sunk cost mechanisms.

GinJinn2: Object detection and segmentation for ecology and evolution

GinJinn2 provides a user-friendly toolbox for deep learning-based object detection and segmentation in ecology and evolution, enabling biologists to automate image analysis tasks.

A hetero-oligomeric remorin-receptor complex regulates plant development

The paper shows that Group 1 remorins form a hetero-oligomeric complex at the plasma membrane, recruiting RIR1 and NILR2 to regulate plant development.

Integration of A Nitrate-Related Signaling Pathway in Rhizobia-Induced Responses During Interactions with Non Legume Host Arabidopsis thaliana

This study shows that rhizobia induce root morphological changes in Arabidopsis, regulated by nitrate signaling pathways involving NLP4, NLP5, and NRT1.1.

A formin-mediated cell wall- plasma membrane- cytoskeleton continuum is required for symbiotic infections in Medicago truncatula

This study identifies SYFO1, a formin protein in Medicago truncatula, which connects the cell wall and cytoskeleton to facilitate rhizobial infection by enabling plasma membrane remodeling and cell polarization.

Distinct signalling routes mediates intercellular and intracellular rhizobial infection in Lotus japonicus

This study identifies distinct genetic and transcriptomic requirements for intercellular rhizobial infection in Lotus japonicus compared to intracellular infection.

Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems

The paper establishes TurboID as the most effective PDL method in plant systems and demonstrates its utility in capturing protein interactomes and structural information.

The Medicago truncatula DREPP protein triggers microtubule fragmentation in membrane nanodomains during symbiotic infections

This study identifies the DREPP protein in Medicago truncatula and shows it regulates microtubule reorganization during rhizobial infection by localizing to membrane nanodomains.

The Evolution of Placental Invasion and Cancer Metastasis are Causally Linked

The paper links placental invasion and cancer metastasis by showing that human stromal cells are more permissive to invasion than bovine cells, supporting the Evolved Levels of Invasibility hypothesis.

Phosphorylation of the exocyst subunit Exo70B2 contributes to the regulation of its function

This study shows that phosphorylation of Exo70B2 regulates its function in secretion and immunity by modulating its localization and interaction with the secretory pathway.

Symbiotic root infections in Medicago truncatula require remorin-mediated receptor stabilization in membrane nanodomains

The paper shows that remorin and SYMREM1 stabilize LYK3 in membrane nanodomains, which is essential for successful symbiotic root infections in Medicago truncatula.