Author

B. Losic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Villanueva· 3 shared M. E. Ahsen· 2 shared X. Chen· 2 shared A. Asgharpour· 1 shared A. Atreja· 1 shared A. Bubie· 1 shared A. Califano· 1 shared A. Castillo· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. Villanueva

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unannotated small RNA clusters in circulating extracellular vesicles detect early stage liver cancer

J. v. Felden, T. G. Lezana, N. Dogra, E. Kozlova, M. E. Ahsen, A. Craig, S. Gifford, B. Wunsch, J. T. Smith, S. Kim, J. E. Diaz, X. Chen, I. Labgaa, P. K. Haber, R. Olsen, , A. Villanueva

The paper identifies a 3-smRC signature from circulating extracellular vesicles that detects early-stage liver cancer with high sensitivity and specificity.

Gut · Oct 1, 2022Peer-reviewedCancer Biology

Landscape of oncoviral genotype and co-infection via Human papilloma andHepatitis B viral tumor in-situ profiling

A. P. Bubie, F. Zoulim, B. Testoni, B. Miles, M. Posner, A. Villanueva, B. Losic

The paper develops a tool to analyze viral genotypes and co-infections in tumors, finding that viral genotype and co-infection significantly impact patient survival and tumor biology.

bioRxiv · Mar 24, 2020Cancer Biology

Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors

A. Bubie, E. G. Kozlova, N. Akers, A. Villanueva, B. Losic

The paper evaluates tumor fitness measures based on neoepitope profiling for predicting immune checkpoint inhibitor response and finds no significant survival benefit beyond tumor mutation burden.

bioRxiv · Jan 13, 2020Cancer Biology

The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies

J. E. L. Diaz, M. E. Ahsen, T. Schaffter, X. Chen, R. B. Realubit, C. Karan, A. Califano, B. Losic, G. Stolovitzky

The paper shows that drug combination transcriptional responses are not simply additive and develops a prediction algorithm with 0.84 AUROC for synergistic combinations.

bioRxiv · Nov 18, 2019Cell Biology

Gut microbiota density influences host physiology and is shaped by host and microbial factors

E. J. Contijoch, G. J. Britton, C. Yang, I. Mogno, Z. Li, R. Ng, S. R. Llewellyn, S. Hira, C. Johnson, K. M. Rabinowitz, R. Barkan, I. Dotan, R. P. Hirten, S.-C. Fu, Y. Luo, , C

The paper examines factors influencing gut microbiota density across mammals, disease states, and interventions, finding host and microbial factors shape density and impact health.

bioRxiv · Jul 12, 2018Microbiology