B. Ni

Physics and physiology determine strategies of bacterial investment in flagellar motility

The paper shows that bacterial investment in flagellar motility is constrained by hydrodynamics and fitness costs, with E. coli strains maximizing motility under nutrient-rich conditions.

Experimental evolution of a reduced bacterial chemotaxis network

This study uses experimental evolution to test the necessity of chemotaxis pathway components in E. coli, finding that core components are essential but some auxiliary proteins can be compensated for.

Attractant and repellent induce opposing changes in the chemoreceptor four-helix bundle ligand-binding domain

The paper identifies malate as a repellent recognized by the MCP2021 chemoreceptor in Comamonas testosteroni and shows how it induces opposing conformational changes compared to the attractant citrate.

PanGu Drug Model: Learn a Molecule Like a Human

The paper introduces PanGu Drug Model, a deep learning architecture for drug discovery that achieves state-of-the-art results in molecule property prediction, generation, and optimization.