B. Van Houten

This study compares single-molecule DNA binding dynamics of purified OGG1 and nuclear extracts using SMADNE, revealing differences in undamaged DNA binding and increased binding lifetime for a catalytically dead variant in nuclear extracts.

This study uses single-molecule fluorescence to show TDG uses multiple diffusion modes to search for DNA lesions and how its structure affects nucleosome interactions.

This study investigates how UV irradiation affects transcription factor DNA-binding specificity using UV-Bind, finding reduced specificity and unexpected increased binding at non-consensus sites.

This study shows UV-nail polish dryer radiation causes DNA damage and somatic mutations in mammalian cells, with mutagenic patterns linked to reactive oxygen species.