SARS-CoV-2 Infection of Salivary Glands Compromises Oral Antifungal InnateImmunity and Predisposes to Oral Candidiasis
A. A. Alfaifi, T. W. Wang, P. Perez, A. A. Sultan, T. F. Meiller, P. Rock, D. Kleiner, D. S. Chertow, S. Hewitt, B. Gasmi, S. Stein, S. Ramelli, D. Martin, B. Warner, M. A. Jabra-Rizk
This study shows SARS-CoV-2 infection reduces histatin-5 in salivary glands, impairing antifungal immunity and increasing Candida albicans prevalence in COVID-19 patients.
bioRxiv · May 13, 2024 · PreprintMicrobiology