Author

C. A. MacRaild

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

D. J. Creek· 2 shared G. Siddiqui· 2 shared A. E. De Paoli· 1 shared A. K. Schuh· 1 shared C. Giannangelo· 1 shared C. T. Webb· 1 shared D. Anderson· 1 shared J. L. Vennerstrom· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

D. J. Creek

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

R. C. S. Edgar, G. Siddiqui, K. Hjerrild, T. R. Malcolm, N. B. Vinh, C. T. Webb, C. A. MacRaild, N. A. Counihan, D. J. Creek, P. J. Scammels, S. McGowan, T. F. De Koning-Ward

This study validates PfA-M17 as a novel drug target by showing its essential role in Plasmodium falciparum survival and demonstrating the efficacy of a specific inhibitor.

bioRxiv · Nov 23, 2021Microbiology

Peroxide antimalarial drugs target redox homeostasis in Plasmodium falciparum infected red blood cells

G. Siddiqui, C. Giannangelo, A. E. De Paoli, A. K. Schuh, K. Heimsch, D. Anderson, T. G. Brown, C. A. MacRaild, J. Wu, X. Wang, Y. Dong, J. L. Vennerstrom, K. Becker, D. J. Creek

This paper identifies redox-related protein targets of peroxide antimalarials using chemoproteomics and confirms their impact on redox homeostasis in Plasmodium falciparum.

bioRxiv · Sep 10, 2021Pharmacology & Toxicology