Cancer BiologybioRxiv
RNA binding kinase UHMK1 regulates therapy induced metabolic adaptation in BRAFV600 melanoma
L. K. Smith, T. Parmenter, M. Kleinschmidt…·G. A. McArthur
The paper identifies UHMK1 as a regulator of metabolic adaptation in BRAFV600 melanoma under targeted therapy, showing its role in mRNA transport and translation and its impact on therapy resistance.
DOI 10.1038/s41467-022-28705-x