Author

C. Ashby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Dogan· 1 shared A. Hoering· 1 shared A. M. Lesokhin· 1 shared A. Makohon-Moore· 1 shared A. Mikulasova· 1 shared A. Rosenthal· 1 shared A. Thakurta· 1 shared B. A. Walker· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Dogan

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2 papers

Recent·Most cited

Accelerated single cell seeding in relapsed multiple myeloma

H. J. Landau, V. Yellapantula, B. J. Diamond, E. H. Rustad, K. Maclachlan, G. Gundem, J. Medina-Martinez, J. E. Arango Ossa, M. Levine, Y. Zhou, K. L. Rajya, P. Baez, M. Attiyeh, A. Makohon-Moore, L. Zhang, , F. Maura

This study uses whole genome sequencing to show that relapsed multiple myeloma exhibits accelerated systemic seeding driven by chemotherapy-induced mutations and clonal expansion of single myeloma cells.

bioRxiv · Feb 25, 2020Cancer Biology

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma

A. Mikulasova, C. Ashby, R. G. Tytarenko, P. Qu, A. Rosenthal, J. A. Dent, K. R. Ryan, M. A. Bauer, C. P. Wardell, A. Hoering, K. Mavrommatis, M. Trotter, S. Deshpande, S. Yaccoby, E. Tian, , B. A. Walker

The paper identifies MYC rearrangements in multiple myeloma, showing they are complex and linked to overexpression of MYC and PVT1 through distinct DNA repair mechanisms.

bioRxiv · Jun 24, 2019Cancer Biology