A. Dogan

Short-stranded zein fibers for muscle tissue engineering in alginate-based hydrogels

This study shows that adding electrospun short-stranded zein fibers to alginate hydrogels improves muscle precursor cell alignment and myogenic differentiation, enhancing muscle tissue formation in cultivated meat systems.

Optimisation of cell fate determination for cultured muscle differentiation

This study identifies key pathways for improving muscle cell differentiation in vitro, achieving near-complete fusion and enhanced muscle protein production in bioartificial constructs.

Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

The paper develops a single-cell MRD assay that detects residual leukemic clones with high sensitivity and reveals clonal architecture in AML.

Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition

The paper uses whole genome sequencing to identify two distinct myeloma precursor conditions, progressive and stable, based on genomic features.

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

This study identifies pDC-AML as a distinct AML subset with high RUNX1 mutations and pDC transcriptional features, suggesting CD123 targeting as a therapeutic strategy.

Accelerated single cell seeding in relapsed multiple myeloma

This study uses whole genome sequencing to show that relapsed multiple myeloma exhibits accelerated systemic seeding driven by chemotherapy-induced mutations and clonal expansion of single myeloma cells.