Author

C. B. Borg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:electrophysiology· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. A. Heusser· 2 shared C. Lund· 1 shared D. Weis· 1 shared E. P. Bennett· 1 shared I. Galleano· 1 shared J. Andersen· 1 shared J. Colding· 1 shared K. Stromgaard· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

S. A. Heusser

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2 papers

Recent·Most cited

Conformational decoupling in acid-sensing ion channels uncovers mechanism and stoichiometry of PcTx1-mediated inhibition

S. A. Heusser, C. B. Borg, J. Colding, S. A. Pless

This study investigates the mechanism and stoichiometry of PcTx1 inhibition of ASIC1a using voltage-clamp fluorometry and subunit concatenation, revealing multiple binding modes and conformational changes.

bioRxiv · Jun 21, 2021Biophysics

Mechanism and site of action of big dynorphin on ASIC1a

C. B. Borg, N. Braun, S. A. Heusser, Y. Bay, D. Weis, I. Galleano, C. Lund, W. Tian, L. M. Haugaard-Kedstroem, E. P. Bennett, T. Lynagh, K. Stromgaard, J. Andersen, S. Pless

This study identifies the binding site and mechanism of big dynorphin on ASIC1a, revealing the acidic pocket as the interaction site and highlighting its potential for therapeutic development.

Proceedings of the National Academy of Sciences · Mar 12, 2020Peer-reviewedBiophysics