Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
D. Sarkar, I. Galleano, S. A. Heusser…·S. A. Pless
This study uses semisynthesis to investigate the role of a conserved lysine in ASIC1a function, showing its importance in activation and desensitization.
S. A. Heusser, C. B. Borg, J. Colding, S. A. Pless
This study investigates the mechanism and stoichiometry of PcTx1 inhibition of ASIC1a using voltage-clamp fluorometry and subunit concatenation, revealing multiple binding modes and conformational changes.
C. Bergh, S. A. Heusser, R. J. Howard, E. Lindahl
The paper constructs Markov state models of GLIC channel gating using enhanced sampling and functional recordings, revealing protonation and mutation effects on conformational transitions and symmetrization.
C. B. Borg, N. Braun, S. A. Heusser…·S. Pless
This study identifies the binding site and mechanism of big dynorphin on ASIC1a, revealing the acidic pocket as the interaction site and highlighting its potential for therapeutic development.