Author

C. Basier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Canal· 3 shared F. Weissmann· 3 shared J. F. Curran· 3 shared J. F. Diffley· 3 shared K. Labib· 3 shared M. Howell· 3 shared M. Wu· 3 shared R. Beale· 3 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

B. Canal

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Rates of global cellular translation and transcription during cell growth and the cell cycle in fission yeast.

C. Basier, P. Nurse

This study measures global translation and transcription in fission yeast during growth and the cell cycle, finding translation scales with size and varies with cell cycle stages.

bioRxiv · Oct 17, 2022 · PreprintCell Biology

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of nsp5 Main Protease

C. Basier, R. Beale, G. Bineva-Todd, B. Canal, J. F. Curran, T. D. Deegan, J. F. Diffley, R. Fujisawa, M. Howell, D. Joshi, K. Labib, C. T. Lim, J. Milligan, H. Nagaraj, N. O'Reilly, , T. U. Zeisner

This study identifies small molecule inhibitors of SARS-CoV-2 nsp5 main protease, finding calpain inhibitor I and peptidyl fluoromethylketones with potent antiviral activity.

bioRxiv · Apr 7, 2021Biochemistry

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease

C. Basier, S. Basu, R. Beale, A. P. Bertolin, B. Canal, J. F. Curran, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, A. W. McClure, J. Milligan, E. Roberts, , J. Zeng

This study identifies patulin and aurintricarboxylic acid as inhibitors of SARS-CoV-2 nsp14 exoribonuclease, showing antiviral activity in cell culture.

bioRxiv · Apr 7, 2021Biochemistry

Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase

C. Basier, S. Basu, R. Beale, B. Canal, V. H. Cowling, J. F. Curran, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, C. T. Lim, T. Mak, A. W. McClure, , T. U. Zeisner

This study identifies four small molecule inhibitors of SARS-CoV-2 nsp14 RNA cap methyltransferase, with three showing synergy with remdesivir in antiviral assays.

bioRxiv · Apr 7, 2021Bioengineering

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems

A. Bernheim, A. Calvo Villamanan, C. Basier, E. P. C. Rocha, M. Touchon, D. Bikard

The paper investigates the interaction between NHEJ repair and type II-A CRISPR-Cas systems, finding that Csn2 inhibits NHEJ while NHEJ does not affect CRISPR-Cas.

bioRxiv · Aug 18, 2017Microbiology