Establishment of a pig influenza challenge model for evaluation of monoclonal antibody delivery platforms
A. McNee, T. Smith, B. Holzer, C. Becky, E. Bessell, G. Guibinga, H. Brown, K. Schultheis, P. Fisher, S. Ramos, A. Nunez, M. Bernard, V. Martini, T. Chrun, Y. Xiao, , E. Tchilian
This study establishes a pig influenza model to evaluate monoclonal antibody efficacy against H1N1, showing dose-dependent reduction in viral load and lung pathology.
bioRxiv · Mar 12, 2020Immunology