Author

D. Bialy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:chicken / avian· 3 Organism:mouse· 3 Assay:metagenomics· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

H. Shelton· 6 shared C. Conceicao· 3 shared D. Bailey· 3 shared I. Dietrich· 3 shared K. Chrzastek· 3 shared N. Thakur· 3 shared P. Hollinghurst· 3 shared P. Stevenson-Leggett· 3 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersMicrobiology

H. Shelton

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Alteration of the chicken upper respiratory microbiota following H9N2 avian influenza virus infection

T. Davis, D. Bialy, J. Leng, R. La Ragione, H. Shelton, K. Chrzastek

This study examines how H9N2 avian influenza virus infection affects the upper respiratory microbiota diversity and composition in chickens, finding reduced alpha diversity and persistent microbiota changes during recovery.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

A random priming amplification method for whole genome sequencing of SARS-CoV-2 and H1N1 influenza A virus.

K. Chrzastek, C. Tennakoon, D. Bialy, G. L. Freimanis, J. Flannery, H. Shelton

This paper compares random priming amplification methods for whole genome sequencing of SARS-CoV-2 and H1N1 influenza A virus, finding that the SISPA method is most effective for non-targeted sequencing.

bioRxiv · Jun 25, 2021 · PreprintMicrobiology

Low pathogenic avian influenza virus infection retards colon microbiome diversification in two different chicken lines

K. Chrzastek, J. Leng, M. K. Zakaria, D. Bialy, R. La Ragione, H. Shelton

This study shows that low pathogenic avian influenza virus infection reduces colon microbiome diversity in two chicken breeds, delaying its recovery.

bioRxiv · Mar 15, 2021Microbiology

Defining functional neuraminidase inhibitor drug resistance motifs in avian influenza viruses and the consequential impact on virus fitness in chicken cells.

D. Bialy, H. Shelton

This study investigates NAI resistance mutations in avian influenza viruses and their impact on virus fitness in chicken cells, finding strain-specific effects and compensatory mutations in HA.

Antiviral Research · Oct 1, 2020Peer-reviewedMicrobiology

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

T. K. Tan, P. Rijal, R. Rahikainen, A. Keeble, L. Schimanski, S. Hussain, R. Harvey, J. Hayes, J. Edwards, R. McLean, V. Martini, M. Pedrera, N. Thakur, C. Conceicao, I. Dietrich, , R. Owens

This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.

bioRxiv · Aug 31, 2020Immunology

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

S. P. Graham, R. K. McLean, A. J. Spencer, S. Belij-Rammerstorfer, D. Wright, M. Ulaszewska, J. C. Edwards, J. W. P. Hayes, V. Martini, N. Thakur, C. Conceicao, I. Dietrich, H. Shelton, R. Waters, A. Ludi, , T. Lambe

This study evaluates the immunogenicity of single and booster doses of the ChAdOx1 nCoV-19 vaccine in mice and pigs, finding that a booster significantly enhances antibody responses, especially in pigs.

bioRxiv · Jun 20, 2020Immunology

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

C. Conceicao, N. Thakur, S. Human, J. T. Kelly, L. Logan, D. Bialy, S. Bhat, P. Stevenson-Leggett, A. Zagrajek, P. Hollinghurst, M. Varga, C. Tsirigoti, J. Hammond, H. J. Maier, E. Bickerton, , D. Bailey

This study shows SARS-CoV-2 Spike protein can bind to ACE2 receptors from multiple mammals, indicating broad host tropism and potential for zoonotic transmission.

bioRxiv · Jun 17, 2020Microbiology