Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria
S.-I. Murtada, Y. Kawamura, C. Cavinato, M. Wang, A. B. Ramachandra, B. Spronck, G. Tellides, J. Humphrey
This study links smooth muscle cell death to osteochondrogenic changes and vascular disease in progeria, identifying a sequence of pathological events leading to cardiovascular complications.
bioRxiv · Jan 10, 2023 · PreprintBioengineering