C. D. Dunn

Phosphate Starvation Signaling Increases Mitochondrial Membrane Potential through Respiration-independent Mechanisms

The paper shows phosphate starvation increases mitochondrial membrane potential through respiration-independent mechanisms in yeast and mammalian cells.

Modeling Adsorption, Conformation, and Orientation of the Fis1 Tail Anchor at the Mitochondrial Outer Membrane

The paper models the adsorption, conformation, and orientation of the Fis1 tail anchor at the mitochondrial outer membrane, supporting monotopic insertion without translocation machinery.

A novel approach to the detection of unusual mitochondrial protein change suggests low basal metabolism of ancestral anthropoids

This paper develops a method to detect rapid mitochondrial protein substitutions and finds reduced cellular metabolism in ancestral anthropoids.

SequenceBouncer: A method to remove outlier entries from a multiple sequence alignment

SequenceBouncer identifies and removes outlier sequences from multiple sequence alignments using Shannon entropy values, improving the reliability of downstream phylogenetic analyses.

An unusual amino acid substitution within hummingbird cytochrome c oxidase alters a key proton-conducting channel

This paper identifies a unique amino acid substitution in hummingbird cytochrome c oxidase and shows it affects a proton-conducting channel through molecular dynamics simulations.

A bacteria-derived tail anchor localizes to peroxisomes in yeast and mammalian cells

The paper shows that a bacteria-derived tail anchor from E. coli localizes to peroxisomes in yeast and mammalian cells, suggesting its utility in studying peroxisomal targeting mechanisms.

Bacterial tail anchors can target to the mitochondrial outer membrane

The paper investigates whether bacterial tail anchors can target to the mitochondrial outer membrane in yeast, finding that specific bacterial TAs are localized to and inserted in the mitochondrial outer membrane.

Deep mutational scanning reveals characteristics important for targeting of the tail-anchored protein Fis1

The paper uses deep mutational scanning to analyze the tail-anchored domain of Fis1p, revealing that positively charged residues are critical for mitochondrial targeting and that TA length does not dictate organelle specificity.