Author

C. de Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Goenka· 1 shared A. Picado· 1 shared B. Hu· 1 shared C. A. Ferrer· 1 shared C. I. Wells· 1 shared D. Drewry· 1 shared D. Tiek· 1 shared F. Kwarcinski· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Goenka

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2 papers

Recent·Most cited

SGC-CLK-1 (CAF-170) a chemical probe for the Cdc2-Like kinases CLK1, CLK2, and CLK4

D. Tiek, C. I. Wells, M. Schroder, X. Song, C. A. Ferrer, A. Goenka, R. Iglesia, M. Lu, B. Hu, F. Kwarcinski, P. Sintha, C. de Silva, M. A. Hossain, A. Picado, W. Zuercher, , D. Drewry

This paper identifies and characterizes SGC-CLK-1, a potent inhibitor of CLK1, CLK2, and CLK4, showing its selectivity and effects on SR protein phosphorylation and localization.

bioRxiv · Dec 15, 2022 · PreprintCancer Biology

Inhibition of Lipopolysaccharide E. coli-induced acute lung injury by extracted Antidesma bunius (L.) Spreng fruits as compared to Fluticasone Propionate, a corticosteroid

M. N. Munoz, J. Lucero, K. S. H. Benzon, J. I. L. Reyes, C. de Silva, R. C. Delicana, U. A. Tejada, S. Chatterjee, K. Watanabe

This study shows that Bignay fruit extract reduces LPS-induced ALI in mice, comparable to Fluticasone Propionate, by decreasing inflammatory biomarkers and vascular leakage.

bioRxiv · Apr 8, 2021 · PreprintPharmacology & Toxicology