Author

A. Picado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

C. I. Wells· 2 shared M. Schroder· 2 shared S. Knapp· 2 shared W. Zuercher· 2 shared A. D. Axtman· 1 shared A. Goenka· 1 shared A. Stolz· 1 shared B. Hu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C. I. Wells

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2 papers

Recent·Most cited

SGC-CLK-1 (CAF-170) a chemical probe for the Cdc2-Like kinases CLK1, CLK2, and CLK4

D. Tiek, C. I. Wells, M. Schroder, X. Song, C. A. Ferrer, A. Goenka, R. Iglesia, M. Lu, B. Hu, F. Kwarcinski, P. Sintha, C. de Silva, M. A. Hossain, A. Picado, W. Zuercher, , D. Drewry

This paper identifies and characterizes SGC-CLK-1, a potent inhibitor of CLK1, CLK2, and CLK4, showing its selectivity and effects on SR protein phosphorylation and localization.

bioRxiv · Dec 15, 2022 · PreprintCancer Biology

The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification

C. I. Wells, H. Al-Ali, D. M. Andrews, C. R. M. Asquith, A. D. Axtman, M. Chung, I. Dikic, D. Ebner, J. Elkins, P. Ettmayer, C. Fischer, M. Frederiksen, N. S. Gray, S. B. Hatch, S. Knapp, , D. H. Drewry

The paper introduces the Kinase Chemogenomic Set (KCGS), a curated collection of 187 selective kinase inhibitors covering 215 human kinases, for use in cell-based screens.

bioRxiv · Dec 22, 2019Cell Biology