Author

C. Larabell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:metagenomics· 1 Organism:multiple species· 1

Frequent Co-Authors

J.-H. Chen· 3 shared A. Ekman· 2 shared A. S. Holehouse· 2 shared G. McDermott· 2 shared S. Boeynaems· 2 shared V. Weinhardt· 2 shared A. Briner· 1 shared A. D. Gitler· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

J.-H. Chen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease

S. Boeynaems, X. R. Ma, V. Yeong, G. M. Ginell, J.-H. Chen, J. A. Blum, L. Nakayama, A. Sanyal, A. Briner, D. Van Haver, J. Pauwels, A. Ekman, H. B. Schmidt, K. Sundararajan, L. Porta, , A. D. Gitler

The paper identifies a common toxic mechanism in positively charged peptides across species and develops a machine learning tool to detect it.

bioRxiv · Mar 9, 2023 · PreprintCell Biology

An ESCRT-dependent pathway of Nuclear and Cytoplasmic Spatial PQC is coordinated at Nuclear Vacuolar Junctions

E. M. Sontag, F. Morales-Polanco, J.-H. Chen, G. McDermott, P. T. Dolan, D. R. Gestaut, M. A. LeGros, C. Larabell, J. Frydman

The paper identifies an ESCRT-dependent pathway that coordinates nuclear and cytoplasmic protein quality control (PQC) at nuclear-vacuolar junctions, enabling vacuolar clearance of misfolded proteins.

bioRxiv · Dec 1, 2022 · PreprintBiochemistry

Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties

S. Boeynaems, A. S. Holehouse, V. Weinhardt, D. Kovacs, J. Van Lindt, C. Larabell, L. Van Den Bosch, R. Das, P. Tompa, R. V. Pappu, A. Gitler

This study shows that spontaneous interactions between proteins and RNA can form multi-layered condensates with distinct material properties and specific amino acid and RNA sequence dependencies.

bioRxiv · Dec 11, 2018Biophysics

PSF correction in soft x-ray tomography

A. Ekman, V. Weinhardt, J.-H. Chen, G. McDermott, M. Le Gros, C. Larabell

The paper introduces a linear model for soft x-ray tomography that incorporates the 3D PSF to improve reconstruction using iterative schemes, validated on simulated and experimental data.

bioRxiv · Feb 5, 2018Cell Biology