Author

C. Leveque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Organism:rat· 1

Frequent Co-Authors

A. Gontu· 2 shared B. Castillo· 2 shared D. Greenawalt· 2 shared D. W. Bernard· 2 shared E. Salazar· 2 shared F. YOUSSOUF· 2 shared I. M. Bird· 2 shared J. Chen· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Gontu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A role for the V0 sector of the V-ATPase in neuroexocytosis: exogenous V0d blocks complexin and SNARE interactions with V0c

C. LEVEQUE, Y. MAULET, Q. WANG, M. RAME, S. MOCHIDA, M. SANGIARDI, F. YOUSSOUF, C. IBORRA, M. SEAGAR, N. VITALE, O. EL FAR

The paper shows that V0d inhibits V0c interactions with complexin and SNAREs, reducing neurotransmission in neurons.

bioRxiv · Jan 31, 2023 · PreprintCell Biology

Molecular landscape of BoNT/B bound to a membrane-inserted synaptotagmin/ganglioside complex

J. Ramirez-Franco, F. Azzaz, M. Sangiardi, G. Ferracci, F. Youssouf, M. R. Popoff, M. Seagar, C. Leveque, J. Fantini, O. EL FAR

This study presents a model of BoNT/B binding to a synaptotagmin/ganglioside complex in a membrane topology, revealing interactions and reduced sensitivity in Felidae with a synaptotagmin2 variant.

bioRxiv · Oct 18, 2021 · PreprintPharmacology & Toxicology

Limited window for donation of convalescent plasma with high live-virus neutralizing antibodies for COVID-19 immunotherapy

A. Gontu, S. Srinivasan, E. Salazar, M. Surendran Nair, R. H. Nissly, D. Greenawalt, I. M. Bird, C. Herzog, M. J. Ferrari, I. Poojary, R. Katani, S. E. Lindner, A. M. Minns, R. Rossi, P. A. Christensen, , S. V. Kuchipudi

The study evaluates anti-SARS-CoV-2 antibody and neutralizing titer profiles in convalescent plasma samples to determine the optimal donation window for immunotherapy.

bioRxiv · Aug 21, 2020Immunology

Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

E. Salazar, S. V. Kuchipudi, P. A. Christensen, T. N. Eagar, X. Yi, P. Zhao, Z. Jin, S. W. Long, R. J. Olsen, J. Chen, B. Castillo, C. Leveque, D. M. Towers, J. Lavinder, J. D. Gollihar, , J. M. Musser

This study finds a strong correlation between anti-RBD and anti-ECD IgG titers and in vitro virus neutralization titers in convalescent plasma, suggesting these titers can serve as surrogates for neutralizing activity.

bioRxiv · Jun 8, 2020Immunology