Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length
M. Kliszczak, D. Moralli, J. Jankowska…·C. M. Green
This study identifies FAM111B as a regulator of telomere length through interactions with the nuclear pore complex, independent of telomerase, and links its dysfunction to genomic instability in HFP patients.